CLCN7

Description		chloride voltage-gated channel 7
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane Chloride Channel Complex
	Molecular Function	Nucleotide Binding Chloride Channel Activity Protein Binding ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity Chloride:proton Antiporter Activity
	Biological Process	Monoatomic Ion Transport Chloride Transport Response To PH Transepithelial Chloride Transport Transmembrane Transport Chloride Transmembrane Transport Proton Transmembrane Transport
Pathways		Stimuli-sensing channels
Drugs
Diseases		Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Acute anterior uveitis in ankylosing spondylitis ( 32492107) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: AQP7 CD53 CREB3 GDAP1 GET1 KCNN3 LHFPL5 LYVE1 MTDH OPRM1 OSTM1 PACS1 SLC38A7 SLC66A2 TLCD4 TMEM179B
Entrez ID		1186
HPRD ID		04103
Ensembl ID		ENSG00000103249
Uniprot IDs		P51798
PDB IDs		7BXU 7CQ5 7CQ6 7CQ7 7JM7 8HVT
Enriched GO Terms of Interacting Partners?		Membrane Protein-membrane Adaptor Activity Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Positive Regulation Of Deacetylase Activity L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Monoatomic Ion Transport
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