AP3S1

Description		adaptor related protein complex 3 subunit sigma 1
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GO Annotations	Cellular Component	Early Endosome Golgi Apparatus Membrane Membrane Coat AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Presynapse Axon Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Insulin Receptor Signaling Pathway Protein Transport Synaptic Vesicle Coating Vesicle-mediated Transport Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Synaptic Vesicle Recycling Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Melanosome Assembly
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Novel Interacting Genes		8 novel interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3 SRP19
Interacting Genes		8 interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3 SRP19
Entrez ID		1176
HPRD ID		03298
Ensembl ID		ENSG00000177879
Uniprot IDs		F5H459 Q92572
PDB IDs		9C58 9C59 9C5B 9C5C
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Coating Clathrin-coated Vesicle Cargo Loading, AP-3-mediated AP-3 Adaptor Complex Anterograde Synaptic Vesicle Transport Synaptic Vesicle Recycling Membrane Coat Cellular Localization Vesicle Cargo Loading Synaptic Vesicle Transport Vesicle Coating Vacuolar Transport Anterograde Axonal Transport Vesicle Transport Along Microtubule Zinc Ion Import Into Lysosome Vesicle Cytoskeletal Trafficking Intracellular Transport Axon Cytoplasm Axonal Transport Establishment Of Protein Localization Vacuolar Transmembrane Transport Axo-dendritic Transport Organelle Transport Along Microtubule Vesicle Organization Zinc Ion Import Into Organelle Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Localization Lysosomal Transport Melanosome Assembly Intracellular Membrane-bounded Organelle Golgi To Vacuole Transport Protein Transport Platelet Dense Granule Organization Transport Along Microtubule Intracellular Protein Transport Zinc Ion Transmembrane Transport Vesicle-mediated Transport Zinc Ion Transport Cytoskeleton-dependent Intracellular Transport Protein Targeting Microtubule-based Transport Melanosome Organization Pigment Granule Organization SH2 Domain Binding Establishment Of Organelle Localization Golgi Vesicle Transport Protein Targeting To Vacuole Protein Localization To Lysosome Regulation Of Lipid Catabolic Process Early Endosome
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