AGAP3

Description		ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Postsynaptic Density Cell Periphery Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity GTPase Activator Activity GTP Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding
	Biological Process	Cellular Response To Reactive Oxygen Species Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Pathways
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Loneliness ( 27629369)
Novel Interacting Genes		4 novel interacting genes: HOXA1 HSPB1 HUNK MTDH
Interacting Genes		4 interacting genes: HOXA1 HSPB1 HUNK MTDH
Entrez ID		116988
HPRD ID		16707
Ensembl ID		ENSG00000133612
Uniprot IDs		C9J975 E7ESL9 Q86ST5 Q86XV5 Q96P47
PDB IDs		3IHW
Enriched GO Terms of Interacting Partners?		Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior Positive Regulation Of Vasculature Development Positive Regulation Of Angiogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Outer Ear Morphogenesis Embryonic Neurocranium Morphogenesis Regulation Of Vasculature Development Regulation Of Protein Kinase C Signaling Regulation Of Angiogenesis Anterograde Axonal Protein Transport Regulation Of Canonical NF-kappaB Signal Transduction Intercellular Canaliculus Protein Transport Along Microtubule Contractile Muscle Fiber Regulation Of Autophagy Positive Regulation Of Endothelial Cell Chemotaxis
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