NT5C3B

Description		5'-nucleotidase, cytosolic IIIB
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Magnesium Ion Binding 5'-nucleotidase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nucleotide Metabolic Process
Pathways		mRNA decay by 3' to 5' exoribonuclease
Drugs
Diseases
GWAS		Airway wall thickness ( 25517131)
Novel Interacting Genes		1 novel interacting genes: MLH1
Interacting Genes		1 interacting genes: MLH1
Entrez ID		115024
HPRD ID		14475
Ensembl ID		ENSG00000141698
Uniprot IDs		Q969T7
PDB IDs		7ZEE 7ZEG 7ZEH
Enriched GO Terms of Interacting Partners?		Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Guanine/thymine Mispair Binding Male Meiosis Chromosome Segregation Homologous Chromosome Segregation MutLalpha Complex Female Meiosis Chromosome Segregation Mismatch Repair Complex Negative Regulation Of Mitotic Recombination Positive Regulation Of Isotype Switching To IgA Isotypes MutSalpha Complex Binding Regulation Of Mitotic Recombination Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Telomere Localization Mismatched DNA Binding Positive Regulation Of Isotype Switching To IgG Isotypes Spindle Midzone Assembly Somatic Hypermutation Of Immunoglobulin Genes Meiotic Chromosome Segregation Somatic Diversification Of Immune Receptors Via Somatic Mutation Regulation Of Isotype Switching To IgG Isotypes Resolution Of Meiotic Recombination Intermediates ATP-dependent DNA Damage Sensor Activity Nuclear-transcribed MRNA Poly(A) Tail Shortening Isotype Switching Homologous Chromosome Pairing At Meiosis Positive Regulation Of Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response Reciprocal Meiotic Recombination Synaptonemal Complex Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Mismatch Repair Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Regulation Of Isotype Switching Nuclear Lumen Homologous Recombination Positive Regulation Of Immunoglobulin Mediated Immune Response Somatic Diversification Of Immunoglobulins Somatic Cell DNA Recombination Oogenesis Male Meiotic Nuclear Division Negative Regulation Of DNA Recombination Condensed Nuclear Chromosome Male Germ Cell Nucleus Nuclear Chromosome Segregation
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