CD300A

Description		CD300a molecule
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Protein Binding Phosphatidylethanolamine Binding Signaling Receptor Activity
	Biological Process	Immune System Process Cell Adhesion Signal Transduction Negative Regulation Of B Cell Proliferation Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Mast Cell Degranulation Negative Regulation Of MAP Kinase Activity Regulation Of Innate Immune Response Negative Regulation Of Fibroblast Proliferation Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of NK T Cell Activation Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Neutrophil Activation Negative Regulation Of Eosinophil Activation Negative Regulation Of Eosinophil Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Neurological blood protein biomarker levels ( 31320639)
Novel Interacting Genes		7 novel interacting genes: KRT38 KRTAP10-3 NHERF1 SEC22A TMEM218 TMEM60 VMA12
Interacting Genes		7 interacting genes: KRT38 KRTAP10-3 NHERF1 SEC22A TMEM218 TMEM60 VMA12
Entrez ID		11314
HPRD ID		09492
Ensembl ID		ENSG00000167851
Uniprot IDs		J3QKQ4 Q9UGN4
PDB IDs		2Q87
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Microvillus Organization Negative Regulation Of Sodium Ion Transport Gamma-aminobutyric Acid Transport Endomembrane System Golgi Localization Maintenance Of Epithelial Cell Apical/basal Polarity Bile Acid Secretion Maintenance Of Cell Polarity Type 2 Metabotropic Glutamate Receptor Binding Glutathione Transport Plasma Membrane Protein Complex Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Microvillus Assembly Type 3 Metabotropic Glutamate Receptor Binding Regulation Of Renal Phosphate Excretion Establishment Of Golgi Localization Negative Regulation Of Fibroblast Migration Channel Activator Activity Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Gamma-aminobutyric Acid Transmembrane Transporter Activity Dopamine Receptor Binding Beta-2 Adrenergic Receptor Binding Phospholipase C-activating Dopamine Receptor Signaling Pathway Renal Phosphate Ion Absorption Chloride Channel Regulator Activity Intracellular Phosphate Ion Homeostasis Gamma-aminobutyric Acid Import Stereocilium Tip Growth Factor Receptor Binding Cerebrospinal Fluid Circulation Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process Proton-transporting V-type ATPase Complex Assembly Oxysterol Binding Vacuolar Proton-transporting V-type ATPase Complex Cellular Response To Increased Oxygen Levels Oligopeptide Transport Establishment Of Epithelial Cell Apical/basal Polarity Auditory Receptor Cell Stereocilium Organization COPI-coated Vesicle Membrane Protein Catabolic Process In The Vacuole Morphogenesis Of An Epithelium
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