PADI2

Description		peptidyl arginine deiminase 2
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GO Annotations	Cellular Component	Euchromatin Extracellular Region Nucleus Cytoplasm Cytosol Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein-arginine Deiminase Activity Calcium Ion Binding Hydrolase Activity Nuclear Estrogen Receptor Binding Protein Homodimerization Activity Metal Ion Binding Histone Arginine Deiminase Activity Histone H3R26 Arginine Deiminase Activity
	Biological Process	Chromatin Remodeling Substantia Nigra Development Estrogen Receptor Signaling Pathway Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Lymphocyte Chemotaxis Cellular Response To Leukemia Inhibitory Factor
Pathways		Chromatin modifying enzymes Neutrophil degranulation
Drugs		Citrulline
Diseases
GWAS		A body shape index ( 34021172) Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 34021172) Prudent dietary pattern ( 28644415) Rheumatoid arthritis ( 30423114) Visceral fat ( 30942860) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Novel Interacting Genes		2 novel interacting genes: EMC1 PADI4
Interacting Genes		1 interacting genes: RIPK4
Entrez ID		11240
HPRD ID		06396
Ensembl ID		ENSG00000117115
Uniprot IDs		Q9Y2J8
PDB IDs		4N20 4N22 4N24 4N25 4N26 4N28 4N2A 4N2B 4N2C 4N2D 4N2E 4N2F 4N2G 4N2H 4N2I 4N2K 4N2L 4N2M 4N2N 9B96 9B97 9B98
Enriched GO Terms of Interacting Partners?		Histone H3R8 Arginine Deiminase Activity Histone H3R17 Arginine Deiminase Activity Histone H3R2 Arginine Deiminase Activity Histone H3R26 Arginine Deiminase Activity Histone Arginine Deiminase Activity Protein-arginine Deiminase Activity Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Protein Insertion Into ER Membrane Protein-containing Complex
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