KLK8

Description		kallikrein related peptidase 8
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Secretory Granule Serine Protease Inhibitor Complex
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Memory Response To Wounding Keratinocyte Proliferation Neuron Projection Morphogenesis Regulation Of Synapse Organization Synapse Organization Protein Maturation
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Novel Interacting Genes		12 novel interacting genes: CYSRT1 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA RGS2
Interacting Genes		12 interacting genes: CYSRT1 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA RGS2
Entrez ID		11202
HPRD ID		05733
Ensembl ID		ENSG00000129455
Uniprot IDs		A0A0A0MQY9 O60259
PDB IDs		5MS3 5MS4
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Epidermis Development Structural Constituent Of Skin Epidermis Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Tissue Development Intermediate Filament Organization Negative Regulation Of Glycine Import Across Plasma Membrane Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytosol Adenylate Cyclase Inhibitor Activity
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