NUDT5

Description		nudix hydrolase 5
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GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Magnesium Ion Binding RNA Binding Protein Binding Transferase Activity Nucleotidyltransferase Activity Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity ADP-sugar Diphosphatase Activity SnoRNA Binding Identical Protein Binding Protein Homodimerization Activity 8-oxo-dGDP Phosphatase Activity Metal Ion Binding ADP-ribose Diphosphatase Activity 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Nucleoside Phosphate Metabolic Process Nucleotide Metabolic Process Ribonucleoside Diphosphate Catabolic Process D-ribose Catabolic Process Ribose Phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process ATP Generation From Poly-ADP-D-ribose
Pathways		Phosphate bond hydrolysis by NUDT proteins
Drugs
Diseases
GWAS		Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Novel Interacting Genes		6 novel interacting genes: COX5B GATA3 GORASP2 MAPK6 MCM3AP NUDT3
Interacting Genes		6 interacting genes: COX5B GATA3 GORASP2 MAPK6 MCM3AP NUDT3
Entrez ID		11164
HPRD ID		14851
Ensembl ID		ENSG00000165609
Uniprot IDs		Q9UKK9
PDB IDs		2DSB 2DSC 2DSD 3AC9 3ACA 3BM4 3L85 5NQR 5NWH 5QJ4 5QJ5 5QJ6 5QJ7 5QJ8 5QJ9 5QJA 5QJB 5QJC 5QJD 5QJE 5QJF 5QJG 5QJH 5QJI 5QJJ 5QJK 5QJL 5QJM 5QJN 5QJO 5QJP 5QJQ 5QJR 5QJS 5QJT 5QJU 5QJV 5QJW 5QJX 5QJY 5QJZ 5QK0 5QK1 5QK2 5QK3 5QK4 5QK5 5QK6 5QK7 5QK8 5QK9 5QKA 5QKB 5QTL 5QTM 5QTN 5QTO 5QTP 5QTQ 5QTR 5QTS 6GRU 8PTT 8RDZ 8RIY
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Response To X-ray Negative Regulation Of Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Type IV Hypersensitivity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Negative Regulation Of Cell Proliferation Involved In Mesonephros Development Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Pro-T Cell Differentiation Parathyroid Hormone Secretion Septin Cytoskeleton 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Nephric Duct Formation Regulation Of Thyroid Hormone Generation Positive Regulation Of Ureteric Bud Formation Ureter Maturation Positive Regulation Of Thyroid Hormone Generation Mast Cell Differentiation Bis(5'-adenosyl)-pentaphosphatase Activity Diadenosine Polyphosphate Catabolic Process Ureteric Bud Formation Interleukin-2 Receptor Binding Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Cell Proliferation Involved In Kidney Development Immune System Development Transcription Export Complex 2 Parathyroid Gland Development Mesonephric Tubule Formation Ureter Morphogenesis Otic Vesicle Development Nephric Duct Morphogenesis Norepinephrine Biosynthetic Process Histone H3 Acetyltransferase Activity T-helper 2 Cell Differentiation Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of Epithelial Tube Formation Cellular Response To Interferon-alpha 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity Cytochrome-c Oxidase Activity Positive Regulation Of Transcription Regulatory Region DNA Binding
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