PLAAT3

Description		phospholipase A and acyltransferase 3
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Mitochondrion Lysosome Lysosomal Membrane Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Mitochondrial Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Phospholipase Activity Phospholipase A2 Activity Protein Binding Lipid Binding Phospholipase A1 Activity N-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity
	Biological Process	Lipid Metabolic Process Triglyceride Metabolic Process Phospholipid Metabolic Process Peroxisome Organization Phospholipid Biosynthetic Process Response To Bacterium Lipid Catabolic Process Membrane Disassembly Phosphatidylethanolamine Acyl-chain Remodeling Ether Lipid Metabolic Process N-acylphosphatidylethanolamine Metabolic Process Lens Fiber Cell Differentiation Organelle Disassembly Regulation Of Adipose Tissue Development
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI
Drugs
Diseases
GWAS
Novel Interacting Genes		6 novel interacting genes: MARK2 NRIP1 PPP2R1A UBQLN1 UBQLN2 UBQLN4
Interacting Genes		6 interacting genes: MARK2 NRIP1 PPP2R1A UBQLN1 UBQLN2 UBQLN4
Entrez ID		11145
HPRD ID		13671
Ensembl ID		ENSG00000176485
Uniprot IDs		P53816
PDB IDs		2KYT 4DOT 4FA0 4Q95 7C3Z 7C41 7ZOM
Enriched GO Terms of Interacting Partners?		Polyubiquitin Modification-dependent Protein Binding Autophagy Autophagosome Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Regulation Of Proteasomal Protein Catabolic Process Regulation Of Macroautophagy Positive Regulation Of Response To Endoplasmic Reticulum Stress Catabolic Process Macromolecule Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Autophagy Lateral Plasma Membrane Meiotic Spindle Elongation Ovarian Follicle Rupture Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Regulation Of Meiotic Cell Cycle Process Involved In Oocyte Maturation Regulation Of Cellular Response To Stress Modification-dependent Protein Catabolic Process Autophagosome Organization Negative Regulation Of G Protein-coupled Receptor Internalization Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Nuclear Proteasome Complex Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Autophagosome Maturation Proteolysis Involved In Protein Catabolic Process Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape Meiotic Sister Chromatid Cohesion, Centromeric Organelle Assembly Negative Regulation Of Clathrin-dependent Endocytosis Vacuole Organization Microtubule Bundle Mitotic Sister Chromatid Separation Spindle Elongation Cytosolic Proteasome Complex Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Proteolysis Cytoplasmic Vesicle Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Protein Antigen Binding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand K48-linked Polyubiquitin Modification-dependent Protein Binding Chromosome Separation
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