HACL2

Description		2-hydroxyacyl-CoA lyase 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Acetolactate Synthase Complex Membrane
	Molecular Function	Magnesium Ion Binding Catalytic Activity Acetolactate Synthase Activity Protein Binding Lyase Activity Thiamine Pyrophosphate Binding Metal Ion Binding Flavin Adenine Dinucleotide Binding
	Biological Process	Fatty Acid Alpha-oxidation Lipid Metabolic Process Fatty Acid Metabolic Process
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		5 novel interacting genes: ATXN1 CEP76 ECT2 TOM1 XRCC6
Interacting Genes		5 interacting genes: ATXN1 CEP76 ECT2 TOM1 XRCC6
Entrez ID		10994
HPRD ID		16152
Ensembl ID		ENSG00000105135
Uniprot IDs		A1L0T0 M0R026
PDB IDs
Enriched GO Terms of Interacting Partners?		Centralspindlin Complex Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Positive Regulation Of Protein Kinase Activity Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Regulation Of Kinase Activity Cellular Response To Radiation Response To Radiation Response To Ionizing Radiation Cellular Response To Ionizing Radiation Cellular Response To Chemical Stress Positive Regulation Of Cell Differentiation Regulation Of Organelle Organization Positive Regulation Of Protein Phosphorylation Cytosol Cellular Response To X-ray Double-strand Break Repair Via Classical Nonhomologous End Joining Hyperosmotic Salinity Response DNA End Binding Cellular Hyperosmotic Salinity Response Nuclear Telomere Cap Complex DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity Cellular Response To Salt Stress Protein-containing Complex DNA-dependent Protein Kinase Complex Ku70:Ku80 Complex Double-stranded Telomeric DNA Binding Nonhomologous End Joining Complex Poly(G) Binding POZ Domain Binding Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Clathrin Heavy Chain Binding Substrate Localization To Autophagosome Myosin VI Binding Regulation Of Endosome Organization Positive Regulation Of Autophagosome Maturation Nuclear Inclusion Body Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Positive Regulation Of Developmental Process Autophagosome-lysosome Fusion Regulation Of Autophagosome Maturation Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Cellular Hyperosmotic Response
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