SMPDL3A

Description		sphingomyelin phosphodiesterase acid like 3A
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Sphingomyelin Phosphodiesterase Activity Protein Binding Phosphoric Diester Hydrolase Activity Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Metal Ion Binding
	Biological Process	Sphingomyelin Catabolic Process Nucleoside Triphosphate Catabolic Process Negative Regulation Of CGAS/STING Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Malaria ( 31844061)
Novel Interacting Genes		1 novel interacting genes: BRINP1
Interacting Genes		1 interacting genes: BRINP1
Entrez ID		10924
HPRD ID		10244
Ensembl ID		ENSG00000172594
Uniprot IDs		Q92484
PDB IDs		5EBB 5EBE
Enriched GO Terms of Interacting Partners?		Fear Response Short-term Memory Behavioral Fear Response Exploration Behavior Behavioral Defense Response Homeostasis Of Number Of Cells Within A Tissue Reproductive Behavior Vocalization Behavior Maternal Behavior Parental Behavior Central Nervous System Neuron Development Social Behavior Multicellular Organismal Response To Stress Cellular Response To Retinoic Acid Positive Regulation Of Neuron Differentiation Response To Retinoic Acid Neurogenesis Negative Regulation Of Nervous System Development Central Nervous System Neuron Differentiation Negative Regulation Of Neurogenesis Memory Anatomical Structure Homeostasis Tissue Homeostasis Neuron Development Regulation Of Neuron Differentiation Homeostasis Of Number Of Cells Negative Regulation Of Mitotic Cell Cycle Protein Stabilization Brain Development
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