CEACAM8

Description		CEA cell adhesion molecule 8
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane Side Of Membrane
	Molecular Function	Protein Binding Protein Heterodimerization Activity
	Biological Process	Immune Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: CEACAM1 CEACAM6
Interacting Genes		2 interacting genes: CEACAM1 CEACAM6
Entrez ID		1088
HPRD ID		07630
Ensembl ID		ENSG00000124469
Uniprot IDs		B4DLI3 P31997 Q0Z7S6
PDB IDs		2DKS 4WTZ 4Y88 4YIQ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Insulin Receptor Internalization Negative Regulation Of Cytotoxic T Cell Degranulation Negative Regulation Of Hepatocyte Proliferation Apical Plasma Membrane Insulin Catabolic Process Granulocyte Colony-stimulating Factor Signaling Pathway Regulation Of Homophilic Cell Adhesion Negative Regulation Of T Cell Mediated Cytotoxicity Cell-cell Adhesion Bile Acid Transmembrane Transporter Activity Negative Regulation Of Granulocyte Differentiation Common Myeloid Progenitor Cell Proliferation Positive Regulation Of Vasculogenesis Regulation Of Cell-cell Adhesion Cell Surface Filamin Binding Regulation Of Blood Vessel Remodeling Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of Platelet Aggregation Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Heterotypic Cell-cell Adhesion Negative Regulation Of Immune Response To Tumor Cell Regulation Of Hepatocyte Proliferation Regulation Of Granulocyte Differentiation Regulation Of Vasculogenesis Regulation Of Cell Adhesion Insulin Metabolic Process Negative Regulation Of Platelet Activation Negative Regulation Of Vascular Permeability T Cell Receptor Complex Negative Regulation Of Anoikis Negative Regulation Of Fatty Acid Biosynthetic Process Bile Acid And Bile Salt Transport Cell Adhesion Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Anoikis Regulation Of Cell Motility Microvillus Membrane Regulation Of Cell Migration Regulation Of Response To Tumor Cell Wound Healing, Spreading Of Cells Regulation Of Platelet Aggregation Negative Regulation Of T Cell Receptor Signaling Pathway Regulation Of Locomotion Negative Regulation Of Exocytosis Negative Regulation Of T Cell Mediated Immunity Regulation Of Endothelial Cell Differentiation
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