NEU3

Description		neuraminidase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Plasma Membrane Caveola Membrane Early Endosome Membrane Recycling Endosome Membrane
	Molecular Function	Exo-alpha-sialidase Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Alpha-sialidase Activity
	Biological Process	Carbohydrate Metabolic Process Lipid Metabolic Process Ganglioside Catabolic Process Oligosaccharide Catabolic Process Lipid Catabolic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Glycosphingolipid Catabolic Process Negative Regulation Of Clathrin-dependent Endocytosis
Pathways		Sialic acid metabolism Glycosphingolipid catabolism
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: CAV1 GRB2
Interacting Genes		2 interacting genes: CAV1 GRB2
Entrez ID		10825
HPRD ID		05215
Ensembl ID		ENSG00000162139
Uniprot IDs		B4E0V4 E9PI40 E9PMZ3 E9PNK1 E9PR25 Q9UQ49
PDB IDs
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Receptor Internalization Inward Rectifier Potassium Channel Inhibitor Activity Cell Cortex Receptor-mediated Endocytosis Guanyl-nucleotide Exchange Factor Adaptor Activity Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Insulin Receptor Internalization Protein Localization To Basolateral Plasma Membrane Protein Localization To Plasma Membrane Raft Intracellular Nitric Oxide Homeostasis Immune Response-activating Cell Surface Receptor Signaling Pathway Nitric-oxide Synthase Inhibitor Activity Caveolin-mediated Endocytosis Regulation Of Innate Immune Response Protein Kinase Binding Caveolar Macromolecular Signaling Complex Immune Response-regulating Signaling Pathway Endocytosis Activation Of Immune Response Positive Regulation Of Gap Junction Assembly Negative Regulation Of Pinocytosis Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Mammary Gland Involution Protein-macromolecule Adaptor Activity Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Actin Filament-based Process Regulation Of The Force Of Heart Contraction By Chemical Signal Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Hyperoxia Immune Response-activating Signaling Pathway Grb2-EGFR Complex Neurotrophin TRKA Receptor Binding Positive Regulation Of Cellular Component Biogenesis Regulation Of Entry Of Bacterium Into Host Cell Peptidase Activator Activity Caveola Assembly Protein Tyrosine Kinase Inhibitor Activity Regulation Of Lymphocyte Activation Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Cell Adhesion Protein Localization To Membrane Raft Regulation Of Gap Junction Assembly Patched Binding Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Cell-cell Adhesion
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