ZNF274

Description		zinc finger protein 274
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Cholesterol, total ( 25961943) LDL cholesterol ( 25961943) Ovarian cancer ( 30557369)
Novel Interacting Genes		3 novel interacting genes: NGFR SRY TRIM28
Interacting Genes		3 interacting genes: NGFR SRY TRIM28
Entrez ID		10782
HPRD ID		05682
Ensembl ID		ENSG00000171606
Uniprot IDs		A0A0A0MR47 Q96GC6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Hair Follicle Development Positive Regulation Of DNA-templated Transcription Death Receptor Activity Calmodulin Binding Positive Regulation Of Protein Localization To Nucleus Ubiquitin Protein Ligase Binding Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Nerve Growth Factor Binding Neurotrophin Binding Regulation Of Protein Localization To Nucleus Dorsal Aorta Development Ubiquitin-like Protein Ligase Activity Krueppel-associated Box Domain Binding Embryonic Placenta Morphogenesis Convergent Extension Involved In Axis Elongation Chromo Shadow Domain Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Odontogenesis Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Male Gonad Development Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of Protein Localization Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Convergent Extension Male Sex Determination Cell Differentiation Regulation Of Odontogenesis Suppression Of Viral Release By Host Positive Regulation Of Biosynthetic Process Regulation Of Hair Follicle Development Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway SUMO Transferase Activity Genomic Imprinting Detection Of Temperature Stimulus Positive Regulation Of Endothelial Cell Apoptotic Process Sex Determination Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Developmental Process Sex Differentiation Regulation Of Hair Cycle Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Hair Follicle Morphogenesis Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Aorta Development Regulation Of RNA Biosynthetic Process
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