CSPG5

Description		chondroitin sulfate proteoglycan 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Lumen Plasma Membrane Cell Surface Membrane Golgi-associated Vesicle Membrane Lysosomal Lumen Synapse Postsynaptic Membrane Synaptic Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding Growth Factor Activity
	Biological Process	Cytoskeleton Organization Signal Transduction Nervous System Development Cell Differentiation Intracellular Transport Cell Projection Morphogenesis Modulation Of Chemical Synaptic Transmission Glial Cell Projection Elongation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Synaptic Vesicle Exocytosis
Pathways		Glycosaminoglycan-protein linkage region biosynthesis CS-GAG biosynthesis DS-GAG biosynthesis CS/DS degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases
GWAS		Body mass index ( 29273807) Smoking initiation ( 33082346)
Novel Interacting Genes		3 novel interacting genes: CTSA ERBB3 GOPC
Interacting Genes		3 interacting genes: CTSA ERBB3 GOPC
Entrez ID		10675
HPRD ID		08423
Ensembl ID		ENSG00000114646
Uniprot IDs		A0A087WUT8 B7Z2E0 O95196
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuregulin Receptor Activity Negative Regulation Of Chaperone-mediated Autophagy Lumenal Side Of Lysosomal Membrane Negative Regulation Of Anion Channel Activity ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Serine-type Carboxypeptidase Activity Schwann Cell Differentiation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Transport Negative Regulation Of Motor Neuron Apoptotic Process Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Endocardial Cushion Development Negative Regulation Of Protein Localization To Cell Surface Regulation Of Monoatomic Anion Transport Golgi-associated Vesicle Membrane Apical Protein Localization Protein Tyrosine Kinase Activator Activity Molecular Sequestering Activity Trans-Golgi Network Transport Vesicle Schwann Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Striated Muscle Tissue Development ERBB2 Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Transporter Activity Carboxypeptidase Activity Cranial Nerve Development Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Protein Localization To Cell Surface Regulation Of Striated Muscle Tissue Development Growth Factor Binding Regulation Of Muscle Organ Development Nerve Development Positive Regulation Of Calcium-mediated Signaling Mesenchyme Development Golgi To Plasma Membrane Transport Glial Cell Development Epidermal Growth Factor Receptor Signaling Pathway Protein Transport Basal Plasma Membrane Lateral Plasma Membrane
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