P3H3

Description		prolyl 3-hydroxylase 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Catalytic Complex
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Procollagen-proline 3-dioxygenase Activity L-ascorbic Acid Binding Metal Ion Binding Dioxygenase Activity
	Biological Process	Negative Regulation Of Cell Population Proliferation Peptidyl-lysine Hydroxylation Collagen Metabolic Process Collagen Biosynthetic Process
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Ascorbic acid Proline
Diseases
GWAS
Novel Interacting Genes		7 novel interacting genes: KRT31 KRTAP1-3 KRTAP12-3 KRTAP9-2 OS9 TRIM55 TRIM63
Interacting Genes		7 interacting genes: KRT31 KRTAP1-3 KRTAP12-3 KRTAP9-2 OS9 TRIM55 TRIM63
Entrez ID		10536
HPRD ID		10039
Ensembl ID		ENSG00000110811
Uniprot IDs		Q8IVL6
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Glycosylation-dependent Protein Binding Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Retention In ER Lumen Protein Modification By Small Protein Conjugation Hrd1p Ubiquitin Ligase Complex Protein Ubiquitination Diapedesis Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Post-translational Protein Modification Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Muscle Atrophy
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