SEMA4F

Description		ssemaphorin 4F
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Postsynaptic Density Membrane Dendrite Cell Projection Perikaryon Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Neural Crest Cell Migration Cell-cell Signaling Nervous System Development Axon Guidance Cell Differentiation Positive Regulation Of Cell Migration Negative Regulation Of Axon Extension Retinal Ganglion Cell Axon Guidance Negative Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways		RND3 GTPase cycle
Drugs
Diseases
GWAS		Myopia (pathological) ( 22685421)
Novel Interacting Genes		3 novel interacting genes: DLG4 NRP2 SNCA
Interacting Genes		3 interacting genes: DLG4 NRP2 SNCA
Entrez ID		10505
HPRD ID		04748
Ensembl ID		ENSG00000135622
Uniprot IDs		O95754
PDB IDs
Enriched GO Terms of Interacting Partners?		Axon Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Synaptic Vesicle P2Y1 Nucleotide Receptor Binding Positive Regulation Of Synaptic Transmission Cellular Response To Metal Ion Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Regulation Of Norepinephrine Uptake Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Vestibulocochlear Nerve Structural Organization Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Facioacoustic Ganglion Development Regulation Of Synaptic Plasticity Presynapse Locomotory Behavior Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Postsynapse Postsynaptic Membrane Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Ventral Trunk Neural Crest Cell Migration AMPA Glutamate Receptor Clustering NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Endocytosis Chemical Synaptic Transmission Neuroligin Family Protein Binding Negative Regulation Of Dopamine Metabolic Process Regulation Of Synapse Organization Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Catecholamine Metabolic Process Regulation Of Serotonin Uptake Cranial Ganglion Development Trigeminal Nerve Structural Organization Sympathetic Neuron Projection Guidance Neural Crest Cell Migration Involved In Autonomic Nervous System Development Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Trunk Neural Crest Cell Migration Sympathetic Neuron Projection Extension Trigeminal Ganglion Development Response To Metal Ion
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