ZBTB18

Description		zinc finger and BTB domain containing 18
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GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) General risk tolerance (MTAG) ( 30643258) Mercury levels ( 26025379)
Novel Interacting Genes		10 novel interacting genes: DNMT3A DNMT3B FCGR2B LINC02774 MYLIP PAK1 PIK3R3 POMGNT1 TSN ZBTB2
Interacting Genes		10 interacting genes: DNMT3A DNMT3B FCGR2B LINC02774 MYLIP PAK1 PIK3R3 POMGNT1 TSN ZBTB2
Entrez ID		10472
HPRD ID		12231
Ensembl ID		ENSG00000179456
Uniprot IDs		Q99592
PDB IDs		8P2P
Enriched GO Terms of Interacting Partners?		DNA (cytosine-5-)-methyltransferase Activity Catalytic Complex DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates Fc Receptor Signaling Pathway Regulation Of B Cell Antigen Processing And Presentation Cerebellum Development Fc-gamma Receptor Signaling Pathway Immune Complex Clearance By Monocytes And Macrophages Negative Regulation Of Type I Hypersensitivity Negative Regulation Of Antibody-dependent Cellular Cytotoxicity Protein-cysteine Methyltransferase Activity Transferase Activity DNA-methyltransferase Activity Regulation Of Immune Complex Clearance By Monocytes And Macrophages Low-affinity IgG Receptor Activity Negative Regulation Of Cytotoxic T Cell Degranulation Follicular Dendritic Cell Activation Immune Complex Clearance Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity
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