IFITM3

Description		interferon induced transmembrane protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Immune System Process Immune Response Response To Virus Negative Regulation Of Viral Transcription Response To Type II Interferon Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Innate Immune Response Host-mediated Suppression Of Symbiont Invasion Defense Response To Virus Type I Interferon-mediated Signaling Pathway
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252)
Novel Interacting Genes		26 novel interacting genes: ABHD16A AQP6 CD53 ELOVL2 ERGIC3 FAM210B FFAR2 FKBP7 GLP1R GPR37 GPRC5D KIR2DL3 LYPD5 MS4A3 NEDD4 OPRM1 PLP1 PTAFR REEP4 SGPL1 SLC10A1 SLC10A2 SLC16A7 TMEM14B TMEM86B VKORC1
Interacting Genes		26 interacting genes: ABHD16A AQP6 CD53 ELOVL2 ERGIC3 FAM210B FFAR2 FKBP7 GLP1R GPR37 GPRC5D KIR2DL3 LYPD5 MS4A3 NEDD4 OPRM1 PLP1 PTAFR REEP4 SGPL1 SLC10A1 SLC10A2 SLC16A7 TMEM14B TMEM86B VKORC1
Entrez ID		10410
HPRD ID		05719
Ensembl ID		ENSG00000142089
Uniprot IDs		Q01628
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane G Protein-coupled Receptor Activity G Protein-coupled Peptide Receptor Activity Bile Acid:sodium Symporter Activity Endoplasmic Reticulum
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