CACNG2

Description		calcium voltage-gated channel auxiliary subunit gamma 2
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GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Cell Surface Membrane Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Monoatomic Ion Channel Complex Somatodendritic Compartment Neuron Projection Organelle Cerebellar Mossy Fiber Synapse Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Voltage-gated Calcium Channel Activity Calcium Channel Activity Protein Binding Channel Regulator Activity Ionotropic Glutamate Receptor Binding
	Biological Process	Protein Targeting To Membrane Monoatomic Ion Transport Calcium Ion Transport Neuromuscular Junction Development Transmission Of Nerve Impulse Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Response To Calcium Ion Membrane Depolarization Positive Regulation Of Synaptic Transmission, Glutamatergic Membrane Hyperpolarization Eye Blink Reflex Calcium Ion Transmembrane Transport Postsynaptic Neurotransmitter Receptor Diffusion Trapping Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Localization To Basolateral Plasma Membrane Regulation Of AMPA Receptor Activity
Pathways		Presynaptic depolarization and calcium channel opening Trafficking of AMPA receptors LGI-ADAM interactions
Drugs		Ergocalciferol Enflurane Spironolactone Nicardipine Verapamil Ethanol Efonidipine Butamben Bioallethrin
Diseases
GWAS		Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Daytime nap ( 33568662)
Novel Interacting Genes		11 novel interacting genes: APP DLG1 DLG2 DLG3 DLG4 GRIA1 GRIA4 PATJ PRKACA SRPK2 WIPF1
Interacting Genes		11 interacting genes: APP DLG1 DLG2 DLG3 DLG4 GRIA1 GRIA4 PATJ PRKACA SRPK2 WIPF1
Entrez ID		10369
HPRD ID		04220
Ensembl ID		ENSG00000166862
Uniprot IDs		Q9Y698
PDB IDs		6DLZ 6DM0 6DM1 6O9G 6TNO
Enriched GO Terms of Interacting Partners?		Neuromuscular Junction Postsynaptic Density Membrane Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Chemical Synaptic Transmission Trans-synaptic Signaling Synaptic Signaling Cell Communication AMPA Glutamate Receptor Complex Ionotropic Glutamate Receptor Signaling Pathway Ionotropic Glutamate Receptor Binding Ligand-gated Ion Channel Signaling Pathway Cell-cell Signaling Receptor Localization To Synapse Receptor Clustering Glutamate Receptor Signaling Pathway Neuron Projection Signaling Establishment Or Maintenance Of Cell Polarity Protein Localization To Synapse Synaptic Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein Kinase Binding Protein Localization To Cell Junction Kinase Binding Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Cell Projection Modulation Of Excitatory Postsynaptic Potential Regulation Of Membrane Potential Adherens Junction NMDA Selective Glutamate Receptor Signaling Pathway AMPA Glutamate Receptor Activity Modulation Of Chemical Synaptic Transmission Synapse Postsynapse Presynapse Neuron Spine Endocytic Vesicle Membrane GMP Kinase Activity Regulation Of System Process Postsynaptic Density Glutamatergic Synapse Cellular Component Assembly Glutamate-gated Receptor Activity GDP Metabolic Process Regulation Of Monoatomic Ion Transmembrane Transport Juxtaparanode Region Of Axon Acetylcholine Receptor Binding Regulation Of Biological Quality
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