APBB3

Description		amyloid beta precursor protein binding family B member 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Actin Cytoskeleton Membrane Nuclear Body
	Molecular Function	Amyloid-beta Binding Protein Binding Low-density Lipoprotein Particle Receptor Binding Molecular Adaptor Activity
	Biological Process	Regulation Of DNA-templated Transcription Positive Regulation Of Protein Secretion
Pathways
Drugs
Diseases
GWAS		Serum immune biomarker levels ( 32066700)
Novel Interacting Genes		6 novel interacting genes: APLP2 APP EGFR ERBB2 PDPK1 RAB4A
Interacting Genes		6 interacting genes: APLP2 APP EGFR ERBB2 PDPK1 RAB4A
Entrez ID		10307
HPRD ID		04089
Ensembl ID		ENSG00000113108
Uniprot IDs		O95704 Q59EH2 Q96DX9
PDB IDs		2DYQ 2YSC
Enriched GO Terms of Interacting Partners?		Intracellular Signaling Cassette Response To Growth Factor Cellular Response To Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus ERBB Signaling Pathway Response To Epidermal Growth Factor Epidermal Growth Factor Receptor Signaling Pathway Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ERBB2-EGFR Signaling Pathway Transition Metal Ion Binding Platelet Alpha Granule Early Endosome Membrane Receptor Complex Positive Regulation Of Epithelial Cell Proliferation ERBB2 Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Perinuclear Region Of Cytoplasm Endosome Intracellular Signal Transduction Regulation Of Toll-like Receptor Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Phosphate Metabolic Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Protein Localization Receptor Localization To Synapse Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Epithelial Cell Proliferation Glial Cell Development Basal Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Signal Transduction Positive Regulation Of Intracellular Signal Transduction Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of MiRNA Transcription Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Protein Localization Positive Regulation Of Protein Localization To Cell Periphery Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Multivesicular Body, Internal Vesicle Lumen 3-phosphoinositide-dependent Protein Kinase Activity Positive Regulation Of MAPK Cascade Serine-type Endopeptidase Inhibitor Activity Positive Regulation Of Protein Localization To Membrane Regulation Of MiRNA Metabolic Process Protein Kinase Activity Ruffle Membrane Regulation Of Cellular Localization
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