CD96

Description		CD96 molecule
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane
	Molecular Function
	Biological Process	Negative Regulation Of Natural Killer Cell Cytokine Production Inflammatory Response Immune Response Cell Adhesion Cell-matrix Adhesion Response To Lipopolysaccharide Negative Regulation Of Type II Interferon Production
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases		C syndrome, including: Opitz trigonocephaly syndrome; Bohring-Opitz syndrome (BOPS)
GWAS		Anti-adalimumab antibody production in response to treatment in Crohn's disease ( 31043678) Current cigarettes per day in chronic obstructive pulmonary disease ( 21685187)
Novel Interacting Genes		1 novel interacting genes: PVR
Interacting Genes		1 interacting genes: PVR
Entrez ID		10225
HPRD ID		06916
Ensembl ID		ENSG00000153283
Uniprot IDs		E9PEJ1 P40200 Q8WUE2
PDB IDs		6ARQ
Enriched GO Terms of Interacting Partners?		Susceptibility To T Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Cell Adhesion Mediator Activity Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Immune Response To Tumor Cell Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Regulation Of T Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Leukocyte Mediated Cytotoxicity Virus Receptor Activity Negative Regulation Of Innate Immune Response Regulation Of Leukocyte Mediated Cytotoxicity Cell Adhesion Molecule Binding Regulation Of T Cell Mediated Immunity Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Receptor Ligand Activity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Symbiont Entry Into Host Cell Positive Regulation Of Lymphocyte Mediated Immunity Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Leukocyte Mediated Immunity Biological Process Involved In Interaction With Host Adherens Junction Cell Killing Regulation Of Lymphocyte Mediated Immunity Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Negative Regulation Of Immune Response Regulation Of Adaptive Immune Response Positive Regulation Of Immune Effector Process Signaling Receptor Activity Negative Regulation Of Defense Response Positive Regulation Of Innate Immune Response Immune Effector Process Focal Adhesion Regulation Of Innate Immune Response Positive Regulation Of Defense Response
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