EIF1

Description		eukaryotic translation initiation factor 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Multi-eIF Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosomal Small Subunit Binding
	Biological Process	Translation Translational Initiation Regulation Of Translational Initiation Regulation Of Gene Expression Regulation Of Primary Metabolic Process
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		9 novel interacting genes: APP CEBPA EIF4G1 HMGB1 HMGB2 MAPK6 OLFM2 RASA1 UPF2
Interacting Genes		9 interacting genes: APP CEBPA EIF4G1 HMGB1 HMGB2 MAPK6 OLFM2 RASA1 UPF2
Entrez ID		10209
HPRD ID		15449
Ensembl ID		ENSG00000173812
Uniprot IDs		P41567 Q6IAV3
PDB IDs		2IF1 4KZX 4KZY 6YBW 6ZMW 6ZP4 6ZVJ 7A09 7QP6 8PJ1 8PPK 8PPL 8XXN 9BLN
Enriched GO Terms of Interacting Partners?		RAGE Receptor Binding Chemoattractant Activity Positive Regulation Of Developmental Process Regulation Of Developmental Process Positive Chemotaxis Positive Regulation Of Cell Differentiation Supercoiled DNA Binding DNA Geometric Change DNA Topological Change Regulation Of Cell Differentiation DNA Binding, Bending DNA Conformation Change Four-way Junction DNA Binding V(D)J Recombination Positive Regulation Of Defense Response Positive Regulation Of Monocyte Chemotaxis Regulation Of Presynapse Organization Regulation Of Presynapse Assembly DNA-binding Transcription Factor Binding Negative Regulation Of Gene Expression Regulation Of Monocyte Chemotaxis Inflammatory Response To Antigenic Stimulus Condensed Chromosome Response To Steroid Hormone Positive Regulation Of Gene Expression Positive Regulation Of Interferon-beta Production Somatic Cell DNA Recombination Negative Regulation Of Macromolecule Biosynthetic Process Transcription Cis-regulatory Region Binding Defense Response Negative Regulation Of Biosynthetic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Macrophage Activation Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Interleukin-1 Beta Production Protein-containing Complex Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Animal Organ Regeneration RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Eukaryotic Translation Initiation Factor 4F Complex Assembly Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Damaged DNA Binding Positive Regulation Of Myeloid Progenitor Cell Differentiation Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Interferon-beta Production
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