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DHRS2
Description
dehydrogenase/reductase 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Molecular Function
Carbonyl Reductase (NADPH) Activity
Protein Binding
Oxidoreductase Activity
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Biological Process
C21-steroid Hormone Metabolic Process
Negative Regulation Of Cell Population Proliferation
Response To Toxic Substance
Electron Transport Chain
Cellular Response To Oxidative Stress
Myeloid Dendritic Cell Differentiation
Negative Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes
5 novel interacting genes:
APPBP2
EXOSC5
FBXO7
TCEA2
ZHX2
Interacting Genes
5 interacting genes:
APPBP2
EXOSC5
FBXO7
TCEA2
ZHX2
Entrez ID
10202
HPRD ID
07483
Ensembl ID
ENSG00000100867
Uniprot IDs
Q13268
PDB IDs
Enriched GO Terms of Interacting Partners
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Ubiquitin-like Ligase-substrate Adaptor Activity
Macromolecule Catabolic Process
Glial Cytoplasmic Inclusion
Classical Lewy Body
Lewy Body Corona
Lewy Neurite
MRNA Catabolic Process
Nucleoplasm
Catabolic Process
Lewy Body Core
RNA Catabolic Process
Macromolecule Metabolic Process
Exoribonuclease Complex
RNA Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Glutamatergic Neuron Differentiation
Retinal Bipolar Neuron Differentiation
Nucleobase-containing Compound Catabolic Process
Protein Heterodimerization Activity
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cytoplasmic Exosome (RNase Complex)
RRNA Catabolic Process
Exosome (RNase Complex)
Nuclear Exosome (RNase Complex)
RNA Exonuclease Activity
Sno(s)RNA Metabolic Process
Poly(A)-dependent SnoRNA 3'-end Processing
U4 SnRNA 3'-end Processing
Nuclear MRNA Surveillance
DNA Deamination
Nucleolar Exosome (RNase Complex)
Cul2-RING Ubiquitin Ligase Complex
Transcription Elongation Factor Complex
Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
SnRNA 3'-end Processing
Nucleus
Positive Regulation Of Mitophagy
Proteasomal Protein Catabolic Process
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