CDH17

Description		cadherin 17
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GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Adherens Junction Cell Surface Membrane Basolateral Plasma Membrane Catenin Complex Cell Junction
	Molecular Function	Integrin Binding Proton-dependent Oligopeptide Secondary Active Transmembrane Transporter Activity Calcium Ion Binding Protein Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Germinal Center B Cell Differentiation Marginal Zone B Cell Differentiation Oligopeptide Transport Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration B Cell Differentiation Positive Regulation Of Integrin Activation By Cell Surface Receptor Linked Signal Transduction Adherens Junction Organization Oligopeptide Transmembrane Transport Cell-cell Adhesion Mediated By Cadherin Spleen Development Cell-cell Adhesion
Pathways		Adherens junctions interactions
Drugs
Diseases
GWAS		Blood pressure traits (multi-trait analysis) ( 28498854) Coronary artery disease ( 33020668) Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 28498854) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
Novel Interacting Genes		1 novel interacting genes: UBQLN2
Interacting Genes		1 interacting genes: UBQLN2
Entrez ID		1015
HPRD ID		04312
Ensembl ID		ENSG00000079112
Uniprot IDs		Q12864
PDB IDs		6ULM 7CYM 7EV1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of ERAD Pathway Negative Regulation Of Receptor Internalization Regulation Of Clathrin-dependent Endocytosis Regulation Of ERAD Pathway Negative Regulation Of Receptor-mediated Endocytosis Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Autophagosome Assembly Molecular Condensate Scaffold Activity Regulation Of Vacuole Organization Negative Regulation Of Endocytosis Autophagosome Regulation Of Receptor Internalization Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Autophagosome Organization Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of G Protein-coupled Receptor Signaling Pathway Vacuole Organization Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Macroautophagy Response To Endoplasmic Reticulum Stress Regulation Of Organelle Assembly
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