ABCC9

Description		ATP binding cassette subfamily C member 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Plasma Membrane Inward Rectifying Potassium Channel Membrane Sarcomere Potassium Ion-transporting ATPase Complex Protein-containing Complex Sarcolemma
	Molecular Function	Nucleotide Binding Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity ATP-activated Inward Rectifier Potassium Channel Activity Potassium Channel Regulator Activity ATP Hydrolysis Activity ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Transmembrane Transporter Binding Protein-containing Complex Binding Potassium Channel Activator Activity ABC-type Transporter Activity
	Biological Process	MAPK Cascade Action Potential Blood Vessel Development Response To Hypoxia Heart Morphogenesis Vascular Process In Circulatory System Regulation Of Transcription By RNA Polymerase II Potassium Ion Transport Response To Stress Mitochondrion Organization Heart Development Skeletal Muscle Tissue Development Blood Circulation Regulation Of Blood Pressure Response To Xenobiotic Stimulus Gene Expression Response To Activity Fatty Acid Oxidation Response To ATP Response To Potassium Ion Cellular Response To Potassium Ion Response To Decreased Oxygen Levels Vasodilation Regulation Of Membrane Potential Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Response To Estrogen Cellular Respiration Negative Regulation Of Blood Pressure ATP Metabolic Process Fibroblast Proliferation Defense Response To Virus Transmembrane Transport Coronary Vasculature Development Cardiac Conduction Cellular Response To Chemical Stress Response To Oxygen Levels Cellular Response To Calcium Ion Cellular Response To ATP Cellular Response To Xenobiotic Stimulus Potassium Ion Transmembrane Transport Circulatory System Development Oxygen Metabolic Process Cardiac Muscle Cell Contraction Blood Vessel Diameter Maintenance Monoatomic Cation Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport Transport Across Blood-brain Barrier Regulation Of Potassium Ion Transmembrane Transport Response To Peptide Reactive Oxygen Species Biosynthetic Process Response To Hydrogen Sulfide Potassium Ion Import Across Plasma Membrane
Pathways		ATP sensitive Potassium channels ABC-family proteins mediated transport Ion homeostasis Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome
Drugs		ATP Glyburide Nicorandil
Diseases		Atrial fibrillation
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 27680694) Gout ( 22179738) Hippocampal sclerosis of aging ( 24770881) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653 30578418)
Novel Interacting Genes		7 novel interacting genes: EEF1G HSPB2 KCNJ11 KCNJ8 LDHA SOX5 STX1A
Interacting Genes		7 interacting genes: EEF1G HSPB2 KCNJ11 KCNJ8 LDHA SOX5 STX1A
Entrez ID		10060
HPRD ID		03258
Ensembl ID		ENSG00000069431
Uniprot IDs		O60706
PDB IDs
Enriched GO Terms of Interacting Partners?		Inward Rectifying Potassium Channel Response To Resveratrol ATP-activated Inward Rectifier Potassium Channel Activity CAMKK-AMPK Signaling Cascade Response To Stilbenoid Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Ventricular Cardiac Muscle Tissue Development Inward Rectifier Potassium Channel Activity Regulation Of Presynaptic Membrane Potential Presynaptic Active Zone Membrane Response To ATP Determination Of Adult Lifespan Potassium Ion Import Across Plasma Membrane Response To Ischemia Cardiac Muscle Tissue Development Atrioventricular Node Cell Differentiation Myosin Head/neck Binding Voltage-gated Potassium Channel Complex Regulation Of Membrane Potential Inorganic Cation Import Across Plasma Membrane Neurotransmitter Transport Protein Localization To Extracellular Region Potassium Ion-transporting ATPase Complex Synaptic Assembly At Neuromuscular Junction Striated Muscle Tissue Development Cardiac Pacemaker Cell Differentiation Action Potential Establishment Of Protein Localization To Extracellular Region Protein Secretion Sulfonylurea Receptor Binding Monoatomic Ion Channel Complex Glutamate Secretion, Neurotransmission Glucose Metabolic Process Lactate Dehydrogenase Activity Glucose Catabolic Process To Lactate Via Pyruvate Asymmetric Neuroblast Division Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Transmembrane Transporter Binding Somatic Muscle Development Import Across Plasma Membrane Potassium Ion Transmembrane Transport Import Into Cell Response To Purine-containing Compound Muscle Tissue Development L-lactate Dehydrogenase (NAD+) Activity Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Calcium-mediated Signaling
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