TMED7-TICAM2

Description		TMED7-TICAM2 readthrough
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GO Annotations	Cellular Component
	Molecular Function
	Biological Process
Pathways		Caspase activation via Death Receptors in the presence of ligand Toll Like Receptor 4 (TLR4) Cascade MyD88-independent TLR4 cascade TRIF-mediated programmed cell death Neutrophil degranulation Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) IKK complex recruitment mediated by RIP1 TRAF6-mediated induction of TAK1 complex within TLR4 complex IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7
Drugs
Diseases
GWAS		Response to antidepressants (symptom improvement) ( 29160301)
Novel Interacting Genes		1 novel interacting genes: TMEM132D
Interacting Genes		1 interacting genes: TMEM132D
Entrez ID		100302736
HPRD ID
Ensembl ID		ENSG00000251201
Uniprot IDs		A0A0A6YYA0 Q86XR7
PDB IDs		2M1W 9DKI 9DLG
Enriched GO Terms of Interacting Partners?
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