POM121C

Description		POM121 transmembrane nucleoporin C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Nuclear Membrane
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore
	Biological Process	RNA Export From Nucleus Protein Import Into Nucleus Protein Transport MRNA Transport
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Liver enzyme levels (alanine transaminase) ( 33972514) Obesity-related traits ( 23251661) Parental lifespan ( 30642433) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Systolic blood pressure ( 30224653)
Novel Interacting Genes		5 novel interacting genes: APC CHRM3 HINFP MEOX2 STAT5A
Interacting Genes		5 interacting genes: APC CHRM3 HINFP MEOX2 STAT5A
Entrez ID		100101267
HPRD ID		19406
Ensembl ID		ENSG00000272391
Uniprot IDs		B4DDR5 B4DET5
PDB IDs
Enriched GO Terms of Interacting Partners?		Leading Edge Membrane Regulation Of Cell Motility Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cell Migration Beta-catenin Destruction Complex Negative Regulation Of Cyclin-dependent Protein Kinase Activity Regulation Of Locomotion Negative Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Phase Transition Gamma-catenin Binding Positive Regulation Of Protein Localization To Centrosome Regulation Of Cell Cycle Developmental Process Regulation Of Protein Localization To Centrosome Body Fluid Secretion Acetylcholine Binding Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Body Fluid Levels Saliva Secretion Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Somite Specification Positive Regulation Of Transcription By RNA Polymerase II Epithelium Development Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Gamma-delta T Cell Differentiation Regulation Of Mast Cell Differentiation Interleukin-4-mediated Signaling Pathway Taurine Metabolic Process Reelin-mediated Signaling Pathway Epithelial Cell Differentiation Involved In Prostate Gland Development Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Thrombopoietin-mediated Signaling Pathway Negative Regulation Of T-helper 17 Cell Lineage Commitment Interleukin-2-mediated Signaling Pathway Phosphate Ion Binding Negative Regulation Of Mast Cell Apoptotic Process Eosinophil Differentiation Mucosa-associated Lymphoid Tissue Development Gamma-delta T Cell Differentiation Interleukin-9-mediated Signaling Pathway Peyer's Patch Development Luteinization Positive Regulation Of Mast Cell Differentiation
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