GNPDA1

Description		glucosamine-6-phosphate deaminase 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Glucosamine-6-phosphate Deaminase Activity Protein Binding Hydrolase Activity Isomerase Activity Identical Protein Binding
	Biological Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Metabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process Generation Of Precursor Metabolites And Energy Single Fertilization N-acetylneuraminate Catabolic Process
Pathways		Glycolysis
Drugs		Beta-D-Glucose 2-Deoxy-2-Amino Glucitol-6-Phosphate N-acetyl-D-glucosamine-6-phosphate
Diseases
GWAS		Asthma ( 29273806 31959851) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Mean platelet volume ( 32888494) Squamous cell lung carcinoma ( 28604730)
Novel Interacting Genes		5 novel interacting genes: EWSR1 HSP90AB1 MAGEA11 PRTFDC1 STK11
Interacting Genes		5 interacting genes: EWSR1 HSP90AB1 MAGEA11 PRTFDC1 STK11
Entrez ID		10007
HPRD ID		09048
Ensembl ID		ENSG00000113552
Uniprot IDs		P46926
PDB IDs		1NE7
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway HSP90-CDC37 Chaperone Complex Histone Deacetylase Binding Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Hypoxanthine Phosphoribosyltransferase Activity Guanine Salvage Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intracellular Protein-containing Complex ATP-dependent Protein Binding Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Receptor Ligand Inhibitor Activity Aryl Hydrocarbon Receptor Complex Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Telomerase Holoenzyme Complex Assembly LRR Domain Binding Regulation Of Organelle Transport Along Microtubule Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Magnesium Ion Binding Dendrite Extension Positive Regulation Of Vesicle Transport Along Microtubule Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Prostate Gland Development Purine Ribonucleoside Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process Adhesion Of Symbiont To Host Cell Virion Attachment To Host Cell Positive Thymic T Cell Selection Anoikis Purine Nucleoside Monophosphate Catabolic Process Nucleoside Salvage Regulation Of Cellular Response To Growth Factor Stimulus Adhesion Of Symbiont To Host Cellular Response To UV-B Golgi Localization Positive T Cell Selection G1 To G0 Transition Protein Kinase Regulator Activity Histone Methyltransferase Binding Chaperone-mediated Protein Complex Assembly Dynein Axonemal Particle Protein Phosphatase Activator Activity Telomere Maintenance Via Telomerase Positive Regulation Of Protein Localization DNA Polymerase Binding Positive Regulation Of Protein Localization To Cell Surface Thymic T Cell Selection
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