PIEZO1

Description		piezo type mechanosensitive ion channel component 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Lamellipodium Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Cation Channel Activity Protein Binding Mechanosensitive Ion Channel Activity
	Biological Process	Cation Transport Positive Regulation Of Myotube Differentiation Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Regulation Of Membrane Potential Detection Of Mechanical Stimulus Cellular Response To Mechanical Stimulus Cation Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Diverticular disease ( 30177863) Glycated hemoglobin levels ( 34059833) Hair color ( 26926045) Heel bone mineral density ( 30598549) Height ( 28552196 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin A1c levels ( 29403010) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) hemolysis of donated blood (osmotic) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Joint mobility (Beighton score) ( 27182965) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494 28453575 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494 27863252) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494) Remission after antidepressant treatment in major depression ( 33589590) Response to antidepressants (symptom improvement) ( 33589590) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Triglyceride levels in HIV infection ( 33109212) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: FBXO7 TUBB3
Entrez ID		9780
HPRD ID		10945
Ensembl ID		ENSG00000103335
Uniprot IDs		Q92508
PDB IDs
Enriched GO Terms of Interacting Partners?
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