EDEM1

Description		ER degradation enhancing alpha-mannosidase like protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Aggresome Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding Protein Binding Misfolded Protein Binding
	Biological Process	Carbohydrate Metabolic Process Response To Unfolded Protein Ubiquitin-dependent ERAD Pathway Trimming Of Terminal Mannose On C Branch Protein Targeting To ER Ubiquitin-dependent Glycoprotein ERAD Pathway Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Mannose Trimming Involved In Glycoprotein ERAD Pathway
Pathways		XBP1(S) activates chaperone genes ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Alzheimer's disease ( 33074286) Diverticular disease ( 30177863) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Uterine fibroids ( 28836065)
Interacting Genes		4 interacting genes: ARID1A CANX IRS2 PDZD11
Entrez ID		9695
HPRD ID		09644
Ensembl ID		ENSG00000134109
Uniprot IDs		A0A024R2D5 Q92611
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?