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TGS1

Description trimethylguanosine synthase 1
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Cytoplasm
  • Cytosol
  • Cajal Body
  • Small Nuclear Ribonucleoprotein Complex
Molecular Function
  • Protein Binding
  • RNA Methyltransferase Activity
  • RNA Trimethylguanosine Synthase Activity
Biological Process
  • Spliceosomal SnRNP Assembly
  • 7-methylguanosine RNA Capping
  • Ribonucleoprotein Complex Biogenesis
  • 7-methylguanosine Cap Hypermethylation
Pathways
  • RORA activates gene expression
  • BMAL1:CLOCK,NPAS2 activates circadian gene expression
  • snRNP Assembly
  • PPARA activates gene expression
  • PPARA activates gene expression
  • Transcriptional activation of mitochondrial biogenesis
  • Activation of gene expression by SREBF (SREBP)
  • Transcriptional regulation of white adipocyte differentiation
  • Regulation of lipid metabolism by PPARalpha
  • Circadian Clock
  • Cytoprotection by HMOX1
  • Heme signaling
Drugs
Diseases
GWAS
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Height ( 18391951)
  • Serum thyroid-stimulating hormone levels ( 24852370)
Interacting Genes 9 interacting genes: ANKRD28 COIL CREBBP EED EP300 HNF4A NCOA6 NOXA1 ZNF76
Entrez ID 96764
HPRD ID 07567
Ensembl ID ENSG00000137574
Uniprot IDs Q96RS0
PDB IDs 3EGI 3GDH
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025