SLC4A8

Description		solute carrier family 4 member 8
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GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Dendrite Asymmetric Synapse Symmetric Synapse Neuronal Cell Body Membrane Presynaptic Membrane Neuron Projection Terminal Bouton Axon Terminus Glial Cell Projection Hippocampal Mossy Fiber Presynapse Glutamatergic Synapse
	Molecular Function	Inorganic Anion Exchanger Activity Sodium:bicarbonate Symporter Activity Sodium Ion Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Anion:anion Antiporter Activity Transmembrane Transporter Activity
	Biological Process	Bicarbonate Transport Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Ion Homeostasis Modulation Of Chemical Synaptic Transmission Regulation Of Intracellular PH Transmembrane Transport Transport Across Blood-brain Barrier Chloride Transmembrane Transport Positive Regulation Of Synaptic Vesicle Exocytosis
Pathways		Bicarbonate transporters
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Fruit consumption ( 32066663) Problematic alcohol use ( 32451486) Response to antidepressants and depression ( 27622933) White matter lesion progression ( 26451028) White matter lesion progression (adjusted for white matter lesion burden at baseline) ( 26451028)
Interacting Genes		3 interacting genes: CA2 CFTR SLC9A3R1
Entrez ID		9498
HPRD ID		05430
Ensembl ID		ENSG00000050438
Uniprot IDs		Q2Y0W8
PDB IDs		5JHO
Enriched GO Terms of Interacting Partners?
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