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LONP1

Description lon peptidase 1, mitochondrial
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Mitochondrion
  • Mitochondrial Matrix
  • Cytosol
  • Membrane
  • Mitochondrial Nucleoid
Molecular Function
  • Mitochondrial Promoter Sequence-specific DNA Binding
  • Single-stranded DNA Binding
  • Single-stranded RNA Binding
  • ATP-dependent Peptidase Activity
  • Serine-type Endopeptidase Activity
  • Protein Binding
  • ATP Binding
  • ATP Hydrolysis Activity
  • Identical Protein Binding
  • ADP Binding
  • Sequence-specific DNA Binding
  • G-quadruplex DNA Binding
  • DNA Polymerase Binding
Biological Process
  • Mitochondrial Genome Maintenance
  • Response To Hypoxia
  • Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
  • Mitochondrion Organization
  • Aging
  • Response To Hormone
  • Response To Aluminum Ion
  • Mitochondrial DNA Metabolic Process
  • Cellular Response To Oxidative Stress
  • Chaperone-mediated Protein Complex Assembly
  • Proteolysis Involved In Cellular Protein Catabolic Process
  • Oxidation-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Red blood cell count ( 32888494)
  • Red cell distribution width ( 32888494)
Interacting Genes 12 interacting genes: A2M APOE CDC37 CDC42 CYP2C8 ECSIT IFIT3 IFIT5 KEAP1 LOXL4 MAST1 RNF32
Entrez ID 9361
HPRD ID 05689
Ensembl ID ENSG00000196365
Uniprot IDs P36776
PDB IDs 2X36 7KRZ 7KSL 7KSM 7NFY 7NG4 7NG5
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025