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MS4A1

Description membrane spanning 4-domains A1
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GO Annotations Cellular Component
  • Extracellular Space
  • Nucleoplasm
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • External Side Of Plasma Membrane
  • Cell Surface
  • Plasma Membrane Raft
  • Extracellular Exosome
Molecular Function
  • Epidermal Growth Factor Receptor Binding
  • Protein Binding
  • Immunoglobulin Binding
  • MHC Class II Protein Complex Binding
  • Identical Protein Binding
Biological Process
  • Store-operated Calcium Entry
  • Humoral Immune Response
  • Response To Bacterium
  • B Cell Differentiation
  • B Cell Proliferation
  • B Cell Activation
  • B Cell Receptor Signaling Pathway
  • Protein Tetramerization
  • Calcium Ion Import Into Cytosol
Pathways
Drugs
  • Rituximab
  • Ibritumomab tiuxetan
  • Tositumomab
  • Ofatumumab
  • Obinutuzumab
  • Technetium Tc-99m nofetumomab merpentan
  • Ocrelizumab
Diseases
GWAS
  • Recurrent major depressive disorder ( 29317602)
Interacting Genes 41 interacting genes: ACKR2 AQP6 CD40 CERS4 CLEC14A CREB3 CREB3L1 CSNK2A1 CSNK2A2 FAM209A FCRL3 FYN GORAB GPR42 HSD17B11 HSD17B13 IL7R KASH5 LCK LEUTX LMNA LYN MDM2 MFSD14B MMD MTIF3 REEP2 REEP4 RNF19B RNF5 SLC10A1 SLC10A6 SLC18A1 SLC35C2 THAP4 TMEM31 TMEM72 TMEM82 TMPPE TMX2 TSPO2
Entrez ID 931
HPRD ID 00204
Ensembl ID ENSG00000156738
Uniprot IDs A0A024R507 P11836
PDB IDs 1S8B 2OSL 3BKY 3PP4 6VJA 6Y90 6Y92 6Y97 6Y9A
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025