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LARGE1

Description LARGE xylosyl- and glucuronyltransferase 1
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Golgi Apparatus
  • Integral Component Of Golgi Membrane
Molecular Function
  • Acetylglucosaminyltransferase Activity
  • Glucuronosyltransferase Activity
  • Glycosyltransferase Activity
  • Manganese Ion Binding
  • UDP-xylosyltransferase Activity
  • Xylosyltransferase Activity
Biological Process
  • N-acetylglucosamine Metabolic Process
  • Protein Glycosylation
  • Protein O-linked Glycosylation
  • Glycosphingolipid Biosynthetic Process
  • Glycoprotein Biosynthetic Process
  • Protein O-linked Mannosylation
  • Skeletal Muscle Tissue Regeneration
  • Muscle Cell Cellular Homeostasis
  • Skeletal Muscle Organ Development
Pathways
  • Defective LARGE causes MDDGA6 and MDDGB6
  • O-linked glycosylation
Drugs
Diseases
GWAS
  • Age at first birth ( 27798627)
  • Type 2 diabetes ( 29926116)
Interacting Genes 1 interacting genes: DNAH5
Entrez ID 9215
HPRD ID 04665
Ensembl ID ENSG00000133424
Uniprot IDs O95461 X5DR28
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025