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LHX4

Description LIM homeobox 4
Image
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
Molecular Function
  • RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
  • Protein Binding
  • Methyl-CpG Binding
  • Sequence-specific DNA Binding
  • Metal Ion Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Placenta Development
  • Regulation Of Transcription By RNA Polymerase II
  • Motor Neuron Axon Guidance
  • Animal Organ Morphogenesis
  • Medial Motor Column Neuron Differentiation
  • Neuron Differentiation
  • Negative Regulation Of Apoptotic Process
  • Positive Regulation Of Transcription By RNA Polymerase II
Pathways
  • Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS
  • Refractive error ( 32231278)
Interacting Genes 53 interacting genes: ADAMTSL4 ARL2 AXIN1 BANP BOD1L2 CDK3 CENPS-CORT CHCHD2 CORO1B DCAF10 DHRS1 DNAJB13 ERO1A FDX2 GOLGA2 HOXC5 IFT172 IKZF1 INO80B KLHL38 KRT38 KRT40 LDB1 LDB2 LONRF1 MAPRE3 MRS2 MYOZ1 NRF1 ORC6 PARP11 POU1F1 QRICH1 SCAND1 SH2D1A SNRNP25 SNRPA SSX1 TCAP TCF4 TP53BP2 TRAPPC6A TRMT11 TSEN54 TSTD2 TXNDC5 UBQLN1 USP2 WASHC3 YY1 ZBTB2 ZNF354C ZNF76
Entrez ID 89884
HPRD ID 03686
Ensembl ID ENSG00000121454
Uniprot IDs A0A0S2Z5S4 Q969G2
PDB IDs 5HOD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025