NAE1

Description		NEDD8 activating enzyme E1 subunit 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Protein Binding NEDD8 Activating Enzyme Activity Ubiquitin Protein Ligase Binding Protein Heterodimerization Activity
	Biological Process	Signal Transduction Protein Modification By Small Protein Conjugation Mitotic DNA Replication Checkpoint Signaling Regulation Of Apoptotic Process Regulation Of Neuron Apoptotic Process Protein Neddylation Neuron Apoptotic Process
Pathways		Neddylation
Drugs		ATP
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		11 interacting genes: ALG8 APP GARS1 NEDD8 OGT SREBF2 TP53BP2 TRIP12 UBA3 UBE2F UBQLN4
Entrez ID		8883
HPRD ID		04545
Ensembl ID		ENSG00000159593
Uniprot IDs		Q13564
PDB IDs		1R4M 1R4N 1TT5 1YOV 2NVU 3DBH 3DBL 3DBR 3GZN
Enriched GO Terms of Interacting Partners?
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