HELZ2

Description		helicase with zinc finger 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane
	Molecular Function	DNA Binding RNA Binding RNA Helicase Activity Ribonuclease Activity Protein Binding ATP Binding Nuclear Receptor Coactivator Activity Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Positive Regulation Of Transcription By RNA Polymerase II RNA Phosphodiester Bond Hydrolysis
Pathways		RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock Cytoprotection by HMOX1 Heme signaling
Drugs
Diseases
GWAS		Basophil count ( 32888494) Daytime nap ( 33568662) Lymphocyte percentage of white cells ( 27863252) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: PPARA PPARG
Entrez ID		85441
HPRD ID		11459
Ensembl ID		ENSG00000130589
Uniprot IDs		Q9BYK8
PDB IDs
Enriched GO Terms of Interacting Partners?
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