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OFD1

Description OFD1 centriole and centriolar satellite protein
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Nucleus
  • Centrosome
  • Centriole
  • Cytosol
  • Cilium
  • Microtubule Cytoskeleton
  • Membrane
  • Motile Cilium
  • Centriolar Satellite
  • Ciliary Basal Body
Molecular Function
  • Protein Binding
  • Identical Protein Binding
  • Alpha-tubulin Binding
  • Gamma-tubulin Binding
Biological Process
  • Mitotic Cell Cycle
  • Centriole Replication
  • Cilium Assembly
  • Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry
  • Mitotic Spindle Assembly
Pathways
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Hedgehog 'off' state
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes 10 interacting genes: CCSER2 CEP126 EGFL6 EIF6 GPRASP1 LUC7L2 NME7 RAI2 RUVBL1 S100A6
Entrez ID 8481
HPRD ID 02162
Ensembl ID ENSG00000046651
Uniprot IDs A6NF31 E9KL37 O75665
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025