CASQ2

Description		calsequestrin 2
Image
GO Annotations	Cellular Component	Cytoplasm Junctional Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Z Disc Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Calcium Channel Complex
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Regulation Of Heart Rate Detection Of Calcium Ion Striated Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Potassium Ion Transport Sequestering Of Calcium Ion Protein Polymerization Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cardiac Muscle Contraction Regulation Of Membrane Repolarization Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Caffeine Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways		Stimuli-sensing channels Ion homeostasis
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left ventricle wall thickness ( 33495596) Left ventricular global radial strain ( 33495596) Pulse pressure ( 30578418) QRS duration ( 27577874 30012220 27659466)
Interacting Genes		5 interacting genes: ANKRD1 CSNK2A1 CSNK2A2 FBXO7 TRDN
Entrez ID		845
HPRD ID		00256
Ensembl ID		ENSG00000118729
Uniprot IDs		O14958
PDB IDs		2VAF 6OWV 6OWW
Enriched GO Terms of Interacting Partners?
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