CAMKK1

Description		calcium/calmodulin dependent protein kinase kinase 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Intracellular Signal Transduction Positive Regulation Of Protein Kinase Activity
Pathways		CaMK IV-mediated phosphorylation of CREB CaMK IV-mediated phosphorylation of CREB CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde Activation of RAC1 downstream of NMDARs Activation of RAC1 downstream of NMDARs
Drugs		Fostamatinib
Diseases
GWAS		Serum alkaline phosphatase levels ( 33339817) Smoking behavior ( 19247474)
Interacting Genes		9 interacting genes: AKT1 APP CALM1 CAMK1 CAMK1D CAMK4 PRKAA1 SGK1 YWHAG
Entrez ID		84254
HPRD ID		13000
Ensembl ID		ENSG00000004660
Uniprot IDs		J3KPJ3 Q8N5S9
PDB IDs		6CCF 6CD6
Enriched GO Terms of Interacting Partners?
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