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ABRAXAS1

Description abraxas 1, BRCA1 A complex subunit
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Nuclear Body
  • BRCA1-A Complex
Molecular Function
  • Protein Binding
  • Microtubule Binding
  • Polyubiquitin Modification-dependent Protein Binding
Biological Process
  • Double-strand Break Repair
  • Chromatin Organization
  • Mitotic G2 DNA Damage Checkpoint Signaling
  • Attachment Of Spindle Microtubules To Kinetochore
  • Response To Ionizing Radiation
  • Positive Regulation Of DNA Repair
  • Protein K63-linked Deubiquitination
  • Mitotic Spindle Assembly
Pathways
  • Metalloprotease DUBs
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Interacting Genes 6 interacting genes: BRCA1 OGT SUMO2 UBC UIMC1 ZMYM3
Entrez ID 84142
HPRD ID 08584
Ensembl ID ENSG00000163322
Uniprot IDs D6REL5 Q6UWZ7
PDB IDs 4JLU 4U4A 4Y18 4Y2G
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025