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TCL1A

Description TCL1 family AKT coactivator A
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Endoplasmic Reticulum
  • Cytosol
  • Protein-containing Complex
Molecular Function
  • Protein Binding
  • Protein Kinase Binding
  • Identical Protein Binding
  • Protein Serine/threonine Kinase Activator Activity
Biological Process
  • Multicellular Organism Development
  • Positive Regulation Of Cell Population Proliferation
  • Positive Regulation Of Mitochondrial Membrane Potential
  • Positive Regulation Of Protein-containing Complex Assembly
  • Positive Regulation Of Peptidyl-serine Phosphorylation
  • Negative Regulation Of Apoptotic Process
  • Cellular Response To Tumor Necrosis Factor
  • Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Drugs
Diseases
GWAS
  • Adverse response to aromatase inhibitors ( 20876420)
  • Mosaic loss of chromosome Y ( 27064253)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
  • Plateletcrit ( 32888494)
  • Refractive error ( 32231278)
Interacting Genes 38 interacting genes: AKT1 AKT2 AKT3 ATM CADPS CALCOCO2 CARD9 CASP8AP2 CCDC13 CEP55 DDIT4L DNMT3A FLACC1 GOLGA2 H2AW INCA1 LNX1 LNX2 LSM3 NFKBIA NFKBID NIF3L1 NTAQ1 PPP1R13B PRTFDC1 REL TAX1BP1 TCF4 TEPSIN TNKS TP53BP2 TRAF1 TRAF2 TRMT61A TTC33 TXLNA TXLNB WDR47
Entrez ID 8115
HPRD ID 01744
Ensembl ID ENSG00000100721
Uniprot IDs A0A024R6G5 P56279
PDB IDs 1JSG
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025