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DUSP16

Description dual specificity phosphatase 16
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Cytoplasmic Vesicle
Molecular Function
  • Phosphoprotein Phosphatase Activity
  • Protein Tyrosine Phosphatase Activity
  • Protein Binding
  • Protein Tyrosine/threonine Phosphatase Activity
  • Phosphatase Activity
  • MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
  • Protein Serine Phosphatase Activity
  • Protein Threonine Phosphatase Activity
Biological Process
  • Dephosphorylation
  • Negative Regulation Of MAPK Cascade
  • MAPK Export From Nucleus
  • MAPK Phosphatase Export From Nucleus, Leptomycin B Sensitive
Pathways
  • RAF-independent MAPK1/3 activation
  • Negative regulation of MAPK pathway
  • Suppression of autophagy
  • Signaling by MAPK mutants
Drugs
Diseases
GWAS
  • Height ( 31562340)
  • Response to fenofibrate (HDL cholesterol levels) ( 27002377)
  • Systolic blood pressure ( 30578418)
Interacting Genes 10 interacting genes: ERBB4 MAPK1 MAPK10 MAPK11 MAPK14 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 TRIM54
Entrez ID 80824
HPRD ID 09525
Ensembl ID ENSG00000111266
Uniprot IDs A0A024RAR2 Q9BY84
PDB IDs 2VSW 3TG3 4YR8
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025