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WDR61

Description WD repeat domain 61
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Cdc73/Paf1 Complex
  • Transcriptionally Active Chromatin
  • Ski Complex
Molecular Function
  • Protein Binding
Biological Process
  • Transcription Elongation From RNA Polymerase II Promoter
  • Wnt Signaling Pathway
  • Negative Regulation Of Myeloid Cell Differentiation
  • Positive Regulation Of Histone H3-K4 Methylation
  • Histone H3-K4 Trimethylation
  • Positive Regulation Of Histone H3-K79 Methylation
Pathways
  • Formation of RNA Pol II elongation complex
  • mRNA decay by 3' to 5' exoribonuclease
  • RNA Polymerase II Pre-transcription Events
  • RNA Polymerase II Transcription Elongation
  • E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
  • Eyebrow thickness ( 26926045)
  • Hemoglobin levels ( 32327693)
  • Reticulocyte count ( 32888494)
Interacting Genes 12 interacting genes: ACVR1 BARD1 DNAJA4 ERRFI1 EZH2 MCPH1 MSRB3 PRNP SMURF1 TCEA1 TGFBR1 YWHAQ
Entrez ID 80349
HPRD ID 15236
Ensembl ID ENSG00000140395
Uniprot IDs H0YL19 Q9GZS3
PDB IDs 3OW8 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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