STAM

Description		signal transducing adaptor molecule
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GO Annotations	Cellular Component	Cytosol Early Endosome Membrane ESCRT-0 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Phosphatidylinositol Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Signal Transduction Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly
Pathways		EGFR downregulation Metalloprotease DUBs Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell RHOU GTPase cycle Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: ARRB1 HGS JAK1 JAK2 JAK3 MAD1L1 MAP3K1 PJA1 PMEPA1 PPP1CA PPP1CC RFFL STAMBP TIMM8A TRIM54 TRIM55 TRIM63 UBC USP15 USP28 USP8
Entrez ID		8027
HPRD ID		03542
Ensembl ID		ENSG00000136738
Uniprot IDs		B4DZT2 Q92783
PDB IDs		2L0A 3F1I 3LDZ
Enriched GO Terms of Interacting Partners?
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