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CTC1

Description CST telomere replication complex component 1
Image
GO Annotations Cellular Component
  • Chromosome, Telomeric Region
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • CST Complex
Molecular Function
  • Single-stranded DNA Binding
  • Protein Binding
  • Telomeric DNA Binding
  • G-rich Strand Telomeric DNA Binding
Biological Process
  • Telomere Maintenance
  • Cellular Response To DNA Damage Stimulus
  • Regulation Of G2/M Transition Of Mitotic Cell Cycle
  • Telomere Maintenance Via Telomere Lengthening
  • Telomere Capping
  • Negative Regulation Of Telomere Maintenance Via Telomerase
  • Multicellular Organism Growth
  • Positive Regulation Of DNA Replication
  • Positive Regulation Of Fibroblast Proliferation
  • Spleen Development
  • Thymus Development
  • Bone Marrow Development
  • Hematopoietic Stem Cell Proliferation
  • Replicative Senescence
Pathways
  • Polymerase switching on the C-strand of the telomere
  • Telomere C-strand synthesis initiation
Drugs
Diseases
GWAS
  • Bipolar disorder ( 28115744)
  • Telomere length ( 23001564)
Interacting Genes 2 interacting genes: APPBP2 TPP1
Entrez ID 80169
HPRD ID 07980
Ensembl ID ENSG00000178971
Uniprot IDs Q2NKJ3
PDB IDs 5W2L 6W6W
Enriched GO Terms of Interacting Partners?
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