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E2F8

Description E2F transcription factor 8
Image
GO Annotations Cellular Component
  • Chromatin
  • Nucleoplasm
  • Nucleolus
  • Cytosol
  • RNA Polymerase II Transcription Regulator Complex
Molecular Function
  • RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • Cis-regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Repressor Activity
  • DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Factor Activity
  • Protein Binding
  • Identical Protein Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Placenta Development
  • Sprouting Angiogenesis
  • Regulation Of Transcription By RNA Polymerase II
  • Cell Population Proliferation
  • Negative Regulation Of Cytokinesis
  • Positive Regulation Of DNA Endoreduplication
  • Cell Cycle Comprising Mitosis Without Cytokinesis
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Trophoblast Giant Cell Differentiation
  • Chorionic Trophoblast Cell Differentiation
  • Hepatocyte Differentiation
Pathways
  • TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Drugs
Diseases
GWAS
  • Mean reticulocyte volume ( 32888494)
Interacting Genes 8 interacting genes: APP EWSR1 FHL3 LZTR1 MEOX2 STUB1 TFCP2 ZDHHC17
Entrez ID 79733
HPRD ID 10981
Ensembl ID ENSG00000129173
Uniprot IDs A0AVK6
PDB IDs 4YO2
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025