ALG8

Description		ALG8 alpha-1,3-glucosyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Alpha-1,3-mannosyltransferase Activity Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Protein Binding Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity
	Biological Process	Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide-lipid Intermediate Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Mannosylation
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG8 causes ALG8-CDG (CDG-1h)
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Tourette syndrome ( 30818990)
Interacting Genes		16 interacting genes: BIK CLRN1 CREB3 CREB3L1 CYB5R3 FAM209A GPX8 IQGAP2 LMNA MFSD6 NAE1 NARS2 RPS6KA5 RSF1 SAR1A TMEM126B
Entrez ID		79053
HPRD ID		10480
Ensembl ID		ENSG00000159063
Uniprot IDs		A0A024R5K5 Q9BVK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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